ethyl 6-chloro-1H-indole-2-carboxylate

ethyl 6-chloro-1H-indole-2-carboxylate - Names and Identifiers

Name	6-Chloroindole-2-carboxylic acid ethyl ester
Synonyms	6-CHLORO-2-INDOLECARBOXYLIC Ethyl 6-chloroindole-2-carboxylate Ethyl-6-chlor-1H-indol-2-carboxylat Ethyl 6-Chloroindole-2-Carboxylicate ethyl 6-chloro-1H-indole-2-carboxylate 6-CHLORO-2-INDOLECARBOXYLIC METHYL ESTER 6-Chloroindole-2-Carboxylic Acid Ethyl Acid 6-Chloroindole-2-carboxylic acid ethyl ester 6-CHLOROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 1H-Indole-2-carboxylic acid, 6-chloro-, ethyl ester
CAS	27034-51-1
InChI	InChI=1/C11H10ClNO2/c1-2-15-11(14)10-5-7-3-4-8(12)6-9(7)13-10/h3-6,13H,2H2,1H3

ethyl 6-chloro-1H-indole-2-carboxylate - Physico-chemical Properties

Molecular Formula	C11H10ClNO2
Molar Mass	223.66
Density	1.329±0.06 g/cm3(Predicted)
Melting Point	169-171 °C
Boling Point	375.0±22.0 °C(Predicted)
Flash Point	180.594°C
Vapor Presure	0mmHg at 25°C
Appearance	Solid
pKa	14.11±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.63

ethyl 6-chloro-1H-indole-2-carboxylate - Introduction

acid ethyl ester is an organic compound with the chemical formula C11H8ClNO2. It is a white or yellowish solid with a special aromatic odor.

acid ethyl ester has important applications in the fields of pharmaceutical synthesis and organic synthesis. It is an intermediate of indole compounds, which is commonly used in the preparation of biologically active compounds, such as anti-tumor drugs and antibacterial drugs.

The method for preparing acid ethyl ester is generally obtained by reacting indole with 6-chloroindole -2-formic acid, and reacting the product with ethanol to form an esterification product.

Regarding safety information, acid ethyl ester should be handled and used with the following precautions: avoid contact with skin, eyes and mucous membranes, and avoid inhaling its dust or gas. Appropriate personal protective equipment such as lab gloves, goggles and protective clothing should be worn during operation. If accidental exposure occurs, immediately flush the affected area with plenty of water and seek medical help.

Last Update：2024-04-09 20:02:46